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Reduced expression of these enzymes is also associated with more aggressive tumors and poor prognosis 22,23,24,25

All the cell culture reagents for the Normal human primary hepatocyte were purchased from ThermoFisher Scientific

Batula VL, Sun J, Nguyen K, Hortobagyi GN, Andreeff

Alterations in the gut microbiome may influence the expression and activity of the sodium/iodine symporter (NIS), a protein essential for iodine transport into thyroid follicular cells (Nicola et al., 2009)

This approach shows potential for diminishing treatment toxicities and enhancing the treatment results, particularly in patients harbouring genetic modifications that up-regulate the production of oxidative stress